The therapeutic efficacy of the oncolytic virus Delta24-RGD in a murine glioma model depends primarily on antitumor immunity

Oncolytic viruses selectively lyse tumor cells, making these agents a promising treatment modality for glioma. Accumulating data suggest that the immune system plays an important role in the anti-glioma activity of oncolytic viruses. In an immune competent glioma model, the therapeutic effect of the...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Kleijn, Anne, Kloezeman, Jenneke, Treffers-Westerlaken, Elike, Fulci, Giulia, Leenstra, Sieger, Dirven, Clemens, Debets, Reno, Lamfers, Martine
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292709/
https://ncbi.nlm.nih.gov/pubmed/25941622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.955697
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