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TM-04 A TRANSGENIC ZEBRAFISH MODEL FOR GLIOMAS WITH MUTATIONS IN ISOCITRATE DEHYDROGENASE 1
Isocitrate dehydrogenase 1 (IDH1) is a gene that is mutated in about 70-90% of grade II/III glioma patients. Unfortunately, there are very few good model systems for IDH-mutated tumors to functionally examine effects of IDH1 mutations and to test candidate inhibitors. We have therefore generated a t...
שמור ב:
הוצא לאור ב: | Neuro Oncol |
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Main Authors: | , , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Oxford University Press
2014
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218628/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.4 |
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