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TM-04 A TRANSGENIC ZEBRAFISH MODEL FOR GLIOMAS WITH MUTATIONS IN ISOCITRATE DEHYDROGENASE 1
Isocitrate dehydrogenase 1 (IDH1) is a gene that is mutated in about 70-90% of grade II/III glioma patients. Unfortunately, there are very few good model systems for IDH-mutated tumors to functionally examine effects of IDH1 mutations and to test candidate inhibitors. We have therefore generated a t...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218628/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.4 |
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