The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy

بواسطة Liu, Suhu, Marneth, Anna E., Alexe, Gabriela, Walker, Sarah R., Gandler, Helen I., Ye, Darwin Q., Labella, Katherine, Mathur, Radhika, Toniolo, Patricia A., Tillgren, Michelle, Gokhale, Prafulla C., Barbie, David, Mullally, Ann, Stegmaier, Kimberly, Frank, David A.
الحاوية / القاعدة Blood Adv (2018)

Castration resistance in prostate cancer is mediated by the kinase NEK6

بواسطة Choudhury, Atish D., Schinzel, Anna C., Cotter, Maura B., Lis, Rosina T., Labella, Katherine, Lock, Ying Jie, Izzo, Francesca, Guney, Isil, Bowden, Michaela, Li, Yvonne Y., Patel, Jinal, Hartman, Emily, Carr, Steven A., Schenone, Monica, Jaffe, Jacob D., Kantoff, Philip W., Hammerman, Peter S., Hahn, William C.
الحاوية / القاعدة Cancer Res (2016)

Development of Selective Covalent Janus Kinase 3 Inhibitors

بواسطة Tan, Li, Akahane, Koshi, McNally, Randall, Reyskens, Kathleen M. S. E., Ficarro, Scott B., Liu, Suhu, Herter-Sprie, Grit S., Koyama, Shohei, Pattison, Michael J., Labella, Katherine, Johannessen, Liv, Akbay, Esra A., Wong, Kwok-Kin, Frank, David A., Marto, Jarrod A., Look, Thomas A., Arthur, J. Simon C., Eck, Michael J., Gray, Nathanael S.
الحاوية / القاعدة J Med Chem (2015)

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

بواسطة Li, Ji, Choi, Peter S, Chaffer, Christine L, Labella, Katherine, Hwang, Justin H, Giacomelli, Andrew O, Kim, Jong Wook, Ilic, Nina, Doench, John G, Ly, Seav Huong, Dai, Chao, Hagel, Kimberly, Hong, Andrew L, Gjoerup, Ole, Goel, Shom, Ge, Jennifer Y, Root, David E, Zhao, Jean J, Brooks, Angela N, Weinberg, Robert A, Hahn, William C
الحاوية / القاعدة eLife (2018)

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

بواسطة Hong, Andrew L, Tseng, Yuen-Yi, Wala, Jeremiah A, Kim, Won-Jun, Kynnap, Bryan D, Doshi, Mihir B, Kugener, Guillaume, Sandoval, Gabriel J, Howard, Thomas P, Li, Ji, Yang, Xiaoping, Tillgren, Michelle, Ghandi, Mahmhoud, Sayeed, Abeer, Deasy, Rebecca, Ward, Abigail, McSteen, Brian, Labella, Katherine M, Keskula, Paula, Tracy, Adam, Connor, Cora, Clinton, Catherine M, Church, Alanna J, Crompton, Brian D, Janeway, Katherine A, Van Hare, Barbara, Sandak, David, Gjoerup, Ole, Bandopadhayay, Pratiti, Clemons, Paul A, Schreiber, Stuart L, Root, David E, Gokhale, Prafulla C, Chi, Susan N, Mullen, Elizabeth A, Roberts, Charles WM, Kadoch, Cigall, Beroukhim, Rameen, Ligon, Keith L, Boehm, Jesse S, Hahn, William C
الحاوية / القاعدة eLife (2019)