PROSTAGLANDIN H SYNTHASE: RESOLVED AND UNRESOLVED MECHANISTIC ISSUES†

Por Tsai, Ah-Lim, Kulmacz, Richard J.
Publicado em 2009

CYCLOOXYGENASE COMPETITIVE INHIBITORS ALTER TYROSYL RADICAL DYNAMICS IN PROSTAGLANDIN H SYNTHASE-2

Por Wu, Gang, Tsai, Ah-Lim, Kulmacz, Richard J.
Publicado em 2009

High-yield production, purification and characterization of functional human duodenal cytochrome b in an Escherichia coli system

Por Liu, Wen, Wu, Gang, Tsai, Ah-Lim, Kulmacz, Richard J.
Publicado em 2011

PHOSPHOLIPID ACTIONS ON PGHS-1 AND -2 CYCLOOXYGENASE KINETICS

Por Doyen, J. Rand, Yucer, Nur, Lichtenberger, Lenard M., Kulmacz, Richard J.
Publicado em 2007

PEROXIDE-INDUCED RADICAL FORMATION AT TYR385 AND TYR504 IN HUMAN PGHS-1

Por Rogge, Corina E., Liu, Wen, Kulmacz, Richard J., Tsai, Ah-Lim
Publicado em 2009

Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1

Por Liu, Wen, Poole, Elizabeth M., Ulrich, Cornelia M., Kulmacz, Richard J.
Publicado em 2012

The Axial Ligation and Stoichiometry of Heme Centers in Adrenal Cytochrome b(561)

Por Kamensky, Yury, Liu, Wen, Tsai, Ah-Lim, Kulmacz, Richard J., Palmer, Graham
Publicado em 2007

Role of Tyr348 in Tyr385 Radical Dynamics and Cyclooxygenase Inhibitor Interactions in Prostaglandin H Synthase-2

Por Rogge, Corina E., Ho, Bryant, Liu, Wen, Kulmacz, Richard J., Tsai, Ah-Lim
Publicado em 2006

Characterization of the Heme Environment in Arabidopsis thaliana Fatty Acid α-Dioxygenase-1

Por Liu, Wen, Rogge, Corina E., Bambai, Bijan, Palmer, Graham, Tsai, Ah-Lim, Kulmacz, Richard J.
Publicado em 2004

Oxyferryl Heme and Not Tyrosyl Radical Is the Likely Culprit in Prostaglandin H Synthase-1 Peroxidase Inactivation

Por Wu, Gang, Rogge, Corina E., Wang, Jinn-Shyan, Kulmacz, Richard J., Palmer, Graham, Tsai, Ah-Lim
Publicado em 2007

CYCLOOXYGENASE REACTION MECHANISM OF PROSTAGLANDIN H SYNTHASE FROM DEUTERIUM KINETIC ISOTOPE EFFECTS

Por Wu, Gang, Lü, Jian-Ming, van der Donk, Wilfred A., Kulmacz, Richard J., Tsai, Ah-lim
Publicado em 2011

Functional analysis of human thromboxane synthase polymorphic variants

Por Chen, Chung-Ying K, Poole, Elizabeth M, Ulrich, Cornelia M, Kulmacz, Richard J, Wang, Lee-Ho
Publicado no Pharmacogenet Genomics (2012)

Functional and structural roles of residues in the third extra-membrane segment (EM3) of adrenal cytochrome b(561)

Por Liu, Wen, da Silva, Giordano F.Z., Wu, Gang, Palmer, Graham, Tsai, Ah-Lim, Kulmacz, Richard J.
Publicado em 2011

Cyclooxygenase Reaction Mechanism of PGHS ------- Evidence for a Reversible Transition between a Pentadienyl Radical and a New Tyrosyl Radical by Nitric Oxide Trapping

Por Lü, Jian-Ming, Rogge, Corina E., Wu, Gang, Kulmacz, Richard J., van der Donk, Wilfred A., Tsai, Ah-lim
Publicado em 2011

His92 and His110 Selectively Affect Different Heme Centers of Adrenal Cytochrome b(561)

Por Liu, Wen, Rogge, Corina E., da Silva, Giordano F. Z., Shinkarev, Vladimir P., Tsai, Ah-Lim, Kamensky, Yury, Palmer, Graham, Kulmacz, Richard J.
Publicado em 2008

Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and risk of colorectal adenoma

Por Poole, Elizabeth M., Hsu, Li, Xiao, Liren, Kulmacz, Richard J., Carlson, Christopher S., Rabinovitch, Peter S., Makar, Karen W., Potter, John D., Ulrich, Cornelia M.
Publicado em 2010

Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2

Por Tsai, Ah-lim, Wu, Gang, Rogge, Corina E., Lü, Jian-Ming, Peng, Sheng, van der Donk, Wilfred A., Palmer, Graham, Gerfen, Gary J., Kulmacz, Richard J.
Publicado em 2010

Genetic variability in EGFR, Src and HER2 and risk of colorectal adenoma and cancer

Por Poole, Elizabeth M, Curtin, Karen, Hsu, Li, Kulmacz, Richard J, Duggan, David J, Makar, Karen W, Xiao, Liren, Carlson, Christopher S, Slattery, Martha L, Caan, Bette J, Potter, John D, Ulrich, Cornelia M
Publicado em 2011

IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry

Por Seufert, Brenna L., Poole, Elizabeth M., Whitton, John, Xiao, Liren, Makar, Karen W., Campbell, Peter T., Kulmacz, Richard J., Baron, John A., Newcomb, Polly A., Slattery, Martha L., Potter, John D., Ulrich, Cornelia M.
Publicado em 2013

Glutathione Peroxidase (GPX) tagSNPs: Associations with Rectal Cancer but not with Colon Cancer

Por Haug, Ulrike, Poole, Elizabeth M., Xiao, Liren, Curtin, Karen, Duggan, David, Hsu, Li, Makar, Karen W, Peters, Ulrike, Kulmacz, Richard J, Potter, John D, Koepl, Lisel, Caan, Bette J, Slattery, Martha L, Ulrich, Cornelia M
Publicado em 2012