PHOSPHOLIPID ACTIONS ON PGHS-1 AND -2 CYCLOOXYGENASE KINETICS

Cyclooxygenase (COX) catalysis by prostaglandin H synthase (PGHS) is a key control step for regulation of prostanoid biosynthesis. Both PGHS isoforms are integral membrane proteins and their substrate fatty acids readily partition into membranes, but the impact of phospholipids and lipid membranes o...

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Bibliographic Details
Main Authors: Doyen, J. Rand, Yucer, Nur, Lichtenberger, Lenard M., Kulmacz, Richard J.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278380/
https://ncbi.nlm.nih.gov/pubmed/18201917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2007.12.001
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