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Functional analysis of human thromboxane synthase polymorphic variants
BACKGROUND: Thromboxane A synthase (TXAS) metabolizes the cyclooxygenase product prostaglandin (PG) H(2) into thromboxane A(2) (TXA(2)), a potent inducer of blood vessel constriction and platelet aggregation. Non-synonymous polymorphisms in the TBXAS gene have the potential to alter TXAS activity an...
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| Publicado no: | Pharmacogenet Genomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4434599/ https://ncbi.nlm.nih.gov/pubmed/22735388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283562d82 |
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