Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2

Cyclooxygenase catalysis by prostaglandin H synthase (PGHS)-1 and -2 involves reaction of a peroxide-induced Tyr385 radical with arachidonic acid (AA) to form an AA radical that reacts with O(2). The potential for isomeric AA radicals and formation of an alternate tyrosyl radical at Tyr504 complicat...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tsai, Ah-lim, Wu, Gang, Rogge, Corina E., Lü, Jian-Ming, Peng, Sheng, van der Donk, Wilfred A., Palmer, Graham, Gerfen, Gary J., Kulmacz, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073652/
https://ncbi.nlm.nih.gov/pubmed/21421123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2010.11.012
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky