The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation

Por Rothe, Tobias, Ipseiz, Natacha, Faas, Maria, Lang, Stefanie, Perez-Branguli, Francesc, Metzger, Daniel, Ichinose, Hiroshi, Winner, Beate, Schett, Georg, Krönke, Gerhard
Publicado no J Immunol (2017)

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency

Por Taylor, Philip R., Heydeck, Dagmar, Jones, Gareth W., Krönke, Gerhard, Funk, Colin D., Knapper, Steven, Adams, Deborah, Kühn, Hartmut, O'Donnell, Valerie B.
Publicado em 2012

Development of three-dimensional prints of arthritic joints for supporting patients’ awareness to structural damage

Por Kleyer, Arnd, Beyer, Laura, Simon, Christoph, Stemmler, Fabian, Englbrecht, Matthias, Beyer, Christian, Rech, Jürgen, Manger, Bernhard, Krönke, Gerhard, Schett, Georg, Hueber, Axel J.
Publicado no Arthritis Res Ther (2017)

Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility

Por Uhrin, Pavel, Dewerchin, Mieke, Hilpert, Mario, Chrenek, Peter, Schöfer, Christian, Zechmeister-Machhart, Margareta, Krönke, Gerhard, Vales, Anja, Carmeliet, Peter, Binder, Bernd R., Geiger, Margarethe
Publicado em 2000

Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).

Por Zarbock, Alexander, DiStasi, Matthew R., Smith, Emily, Sanders, John, Kronke, Gerhard, Harry, Brian, von Vietinghoff, Sibylle, Buscher, Konrad, Nadler, Jerry L., Ley, Klaus
Publicado em 2009

Runx2 mediated Induction of Novel Targets ST2 and Runx3 Leads to Cooperative Regulation of Hypertrophic Differentiation in ATDC5 Chondrocytes

Por Bonyadi Rad, Ehsan, Musumeci, Giuseppe, Pichler, Karin, Heidary, Maryam, Szychlinska, Marta Anna, Castrogiovanni, Paola, Marth, Egon, Böhm, Christina, Srinivasaiah, Sriveena, Krönke, Gerhard, Weinberg, Annelie, Schäfer, Ute
Publicado no Sci Rep (2017)

12/15-lipoxygenase–mediated enzymatic lipid oxidation regulates DC maturation and function

Por Rothe, Tobias, Gruber, Florian, Uderhardt, Stefan, Ipseiz, Natacha, Rössner, Susanne, Oskolkova, Olga, Blüml, Stephan, Leitinger, Norbert, Bicker, Wolfgang, Bochkov, Valery N., Yamamoto, Masayuki, Steinkasserer, Alexander, Schett, Georg, Zinser, Elisabeth, Krönke, Gerhard
Publicado no J Clin Invest (2015)

Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction

Por Kurow, Olga, Frey, Benjamin, Schuster, Louis, Schmitt, Verena, Adam, Susanne, Hahn, Madelaine, Gilchrist, Derek, McInnes, Iain B., Wirtz, Stefan, Gaipl, Udo S., Krönke, Gerhard, Schett, Georg, Frey, Silke, Hueber, Axel J.
Publicado no Front Immunol (2017)

Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

Por Lucas, Sébastien, Omata, Yasunori, Hofmann, Jörg, Böttcher, Martin, Iljazovic, Aida, Sarter, Kerstin, Albrecht, Olivia, Schulz, Oscar, Krishnacoumar, Brenda, Krönke, Gerhard, Herrmann, Martin, Mougiakakos, Dimitrios, Strowig, Till, Schett, Georg, Zaiss, Mario M.
Publicado no Nat Commun (2018)

TNF-induced structural joint damage is mediated by IL-1

Por Zwerina, Jochen, Redlich, Kurt, Polzer, Karin, Joosten, Leo, Krönke, Gerhard, Distler, Joerg, Hess, Andreas, Pundt, Noreen, Pap, Thomas, Hoffmann, Oskar, Gasser, Juerg, Scheinecker, Clemens, Smolen, Josef S., van den Berg, Wim, Schett, Georg
Publicado em 2007

Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthr...

Por Engdahl, Cecilia, Bondt, Albert, Harre, Ulrike, Raufer, Jasmin, Pfeifle, René, Camponeschi, Alessandro, Wuhrer, Manfred, Seeling, Michaela, Mårtensson, Inga-Lill, Nimmerjahn, Falk, Krönke, Gerhard, Scherer, Hans U., Forsblad-d’Elia, Helena, Schett, Georg
Publicado no Arthritis Res Ther (2018)

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus

Por Biermann, Mona H. C., Boeltz, Sebastian, Pieterse, Elmar, Knopf, Jasmin, Rech, Jürgen, Bilyy, Rostyslav, van der Vlag, Johan, Tincani, Angela, Distler, Jörg H. W., Krönke, Gerhard, Schett, Georg Andreas, Herrmann, Martin, Muñoz, Luis E.
Publicado no Front Immunol (2018)

The involvement of Toll‐like receptor 9 in the pathogenesis of erosive autoimmune arthritis

Por Fischer, Anita, Abdollahi‐Roodsaz, Shahla, Böhm, Christina, Niederreiter, Birgit, Meyer, Brigitte, Yau, Anthony C. Y., Lönnblom, Erik, Joosten, Leo A. B., Koenders, Marije, Lehmann, Christian H. K., Dudziak, Diana, Krönke, Gerhard, Holmdahl, Rikard, Steiner, Günter
Publicado no J Cell Mol Med (2018)

Platelet-derived serotonin links vascular disease and tissue fibrosis

Por Dees, Clara, Akhmetshina, Alfiya, Zerr, Pawel, Reich, Nicole, Palumbo, Katrin, Horn, Angelika, Jüngel, Astrid, Beyer, Christian, Krönke, Gerhard, Zwerina, Jochen, Reiter, Rudolf, Alenina, Natalia, Maroteaux, Luc, Gay, Steffen, Schett, Georg, Distler, Oliver, Distler, Jörg H.W.
Publicado em 2011

Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature

Por Kelkka, Tiina, Kienhöfer, Deborah, Hoffmann, Markus, Linja, Marjo, Wing, Kajsa, Sareila, Outi, Hultqvist, Malin, Laajala, Essi, Chen, Zhi, Vasconcelos, Júlia, Neves, Esmeralda, Guedes, Margarida, Marques, Laura, Krönke, Gerhard, Helminen, Merja, Kainulainen, Leena, Olofsson, Peter, Jalkanen, Sirpa, Lahesmaa, Riitta, Souto-Carneiro, M. Margarida, Holmdahl, Rikard
Publicado no Antioxid Redox Signal (2014)

Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss

Por Harre, Ulrike, Lang, Stefanie C., Pfeifle, René, Rombouts, Yoann, Frühbeißer, Sabine, Amara, Khaled, Bang, Holger, Lux, Anja, Koeleman, Carolien A., Baum, Wolfgang, Dietel, Katharina, Gröhn, Franziska, Malmström, Vivianne, Klareskog, Lars, Krönke, Gerhard, Kocijan, Roland, Nimmerjahn, Falk, Toes, René E. M., Herrmann, Martin, Scherer, Hans Ulrich, Schett, Georg
Publicado no Nat Commun (2015)

Regulation of autoantibody activity by the IL-23–T(H)17 axis determines the onset of autoimmune disease

Por Pfeifle, René, Rothe, Tobias, Ipseiz, Natacha, Scherer, Hans U, Culemann, Stephan, Harre, Ulrike, Ackermann, Jochen A, Seefried, Martina, Kleyer, Arnd, Uderhardt, Stefan, Haugg, Benjamin, Hueber, Axel J, Daum, Patrick, Heidkamp, Gordon F, Ge, Changrong, Böhm, Sybille, Lux, Anja, Schuh, Wolfgang, Magorivska, Iryna, Nandakumar, Kutty S, Lönnblom, Erik, Becker, Christoph, Dudziak, Diana, Wuhrer, Manfred, Rombouts, Yoann, Koeleman, Carolien A, Toes, René, Winkler, Thomas H, Holmdahl, Rikard, Herrmann, Martin, Blüml, Stephan, Nimmerjahn, Falk, Schett, Georg, Krönke, Gerhard
Publicado no Nat Immunol (2016)

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis

Por Lauder, Sarah N., Allen-Redpath, Keith, Slatter, David A., Aldrovandi, Maceler, O’Connor, Anne, Farewell, Daniel, Percy, Charles L., Molhoek, Jessica E., Rannikko, Sirpa, Tyrrell, Victoria J., Ferla, Salvatore, Milne, Ginger L., Poole, Alastair W., Thomas, Christopher P., Obaji, Samya, Taylor, Philip R., Jones, Simon A., de Groot, Phillip G., Urbanus, Rolf T., Hörkkö, Sohvi, Uderhardt, Stefan, Ackermann, Jochen, Jenkins, P. Vince, Brancale, Andrea, Krönke, Gerhard, Collins, Peter W., O’Donnell, Valerie B.
Publicado no Sci Signal (2017)

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

Por Uderhardt, Stefan, Ackermann, Jochen A., Fillep, Tobias, Hammond, Victoria J., Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R., Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Dietel, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W., Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L., Lee, James J., Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O’Donnell, Valerie B., Krönke, Gerhard
Publicado no J Exp Med (2017)

Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

Por Uderhardt, Stefan, Ackermann, Jochen A., Fillep, Tobias, Hammond, Victoria J., Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R., Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Dietel, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W., Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L., Lee, James J., Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O’Donnell, Valerie B., Krönke, Gerhard
Publicado no J Exp Med (2018)