Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss

Immunglobulin G (IgG) sialylation represents a key checkpoint that determines the engagement of pro- or anti-inflammatory Fcγ receptors (FcγR) and the direction of the immune response. Whether IgG sialylation influences osteoclast differentiation and subsequently bone architecture has not been deter...

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Publicado en:Nat Commun
Autores principales: Harre, Ulrike, Lang, Stefanie C., Pfeifle, René, Rombouts, Yoann, Frühbeißer, Sabine, Amara, Khaled, Bang, Holger, Lux, Anja, Koeleman, Carolien A., Baum, Wolfgang, Dietel, Katharina, Gröhn, Franziska, Malmström, Vivianne, Klareskog, Lars, Krönke, Gerhard, Kocijan, Roland, Nimmerjahn, Falk, Toes, René E. M., Herrmann, Martin, Scherer, Hans Ulrich, Schett, Georg
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Pub. Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389255/
https://ncbi.nlm.nih.gov/pubmed/25825024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7651
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