Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

Autoimmunity is complicated by bone loss. In human rheumatoid arthritis (RA), the most severe inflammatory joint disease, autoantibodies against citrullinated proteins are among the strongest risk factors for bone destruction. We therefore hypothesized that these autoantibodies directly influence bo...

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書誌詳細
主要な著者: Harre, Ulrike, Georgess, Dan, Bang, Holger, Bozec, Aline, Axmann, Roland, Ossipova, Elena, Jakobsson, Per-Johan, Baum, Wolfgang, Nimmerjahn, Falk, Szarka, Eszter, Sarmay, Gabriella, Krumbholz, Grit, Neumann, Elena, Toes, Rene, Scherer, Hans-Ulrich, Catrina, Anca Irinel, Klareskog, Lars, Jurdic, Pierre, Schett, Georg
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336988/
https://ncbi.nlm.nih.gov/pubmed/22505457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60975
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