Platelet-derived serotonin links vascular disease and tissue fibrosis

Vascular damage and platelet activation are associated with tissue remodeling in diseases such as systemic sclerosis, but the molecular mechanisms underlying this association have not been identified. In this study, we show that serotonin (5-hydroxytryptamine [5-HT]) stored in platelets strongly ind...

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Detalhes bibliográficos
Main Authors: Dees, Clara, Akhmetshina, Alfiya, Zerr, Pawel, Reich, Nicole, Palumbo, Katrin, Horn, Angelika, Jüngel, Astrid, Beyer, Christian, Krönke, Gerhard, Zwerina, Jochen, Reiter, Rudolf, Alenina, Natalia, Maroteaux, Luc, Gay, Steffen, Schett, Georg, Distler, Oliver, Distler, Jörg H.W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092343/
https://ncbi.nlm.nih.gov/pubmed/21518801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101629
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