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Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis
PURPOSE: Tissue fibrosis caused by pathological activation of fibroblasts with increased synthesis of extracellular matrix components is a major hallmark of systemic sclerosis (SSc). Notch signalling regulates tissue differentiation and pathologic activation of Notch signaling has been implicated in...
में बचाया:
| में प्रकाशित: | Arthritis Rheum |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5175482/ https://ncbi.nlm.nih.gov/pubmed/21312186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30254 |
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