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Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis

Autoimmunity, microangiopathy and tissue fibrosis are hallmarks of systemic sclerosis (SSc). Vascular alterations and reduced capillary density decrease blood flow and impair tissue oxygenation in SSc. Oxygen supply is further reduced by accumulation of extracellular matrix (ECM), which increases di...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beyer, Christian, Schett, Georg, Gay, Steffen, Distler, Oliver, Distler, Jörg HW
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688169/
https://ncbi.nlm.nih.gov/pubmed/19473554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2598
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