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Tie2 as a novel key factor of microangiopathy in systemic sclerosis
BACKGROUND: The angiopoietin(Ang)/Tie2 system is a key regulator of vascular biology. The expression of membrane bound (mb) Tie2 and Ang-1 ensures vessel stability, whereas Ang-2, inducible by vascular endothelial growth factor (VEGF), hypoxia, and inflammation, acts as an antagonist. Tie2 signallin...
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| Publicado no: | Arthritis Res Ther |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5445339/ https://ncbi.nlm.nih.gov/pubmed/28545512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1304-2 |
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