Molecular mechanisms of OLIG2 transcription factor in brain cancer

Por Tsigelny, Igor F., Kouznetsova, Valentina L., Lian, Nathan, Kesari, Santosh
Publicado no Oncotarget (2016)

Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter—Organic anion transporter1 (Oat1)

Por Kouznetsova, Valentina L., Tsigelny, Igor F., Nagle, Megha A., Nigam, Sanjay K.
Publicado em 2011

Key structural features for substrate binding to organic anion transporter 1 (Oat1; slc22a6) identified by global untargeted metabolomics of Oat1null plasma

Por Wikoff, William R., Nagle, Megha A., Kouznetsova, Valentina L., Tsigelny, Igor F., Nigam, Sanjay K.
Publicado em 2011

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer

Por Tsigelny, Igor F., Wheler, Jennifer J., Greenberg, Jerry P., Kouznetsova, Valentina L., Stewart, David J., Bazhenova, Lyudmila, Kurzrock, Razelle
Publicado no Oncotarget (2015)

An All-Atom Model of the Structure of Human Copper Transporter 1

Por Tsigelny, Igor F., Sharikov, Yuriy, Greenberg, Jerry P., Miller, Mark A., Kouznetsova, Valentina L., Larson, Christopher A., Howell, Stephen B.
Publicado em 2012

DEVELOPMENT OF NOVEL SMALL MOLECULES THAT TARGET GLIOBLASTOMA STEM CELLS

Por Kesari, Santosh, Tsigelny, Igor F., Mukthavaram, Rajesh, Kouznetsova, Valentina L., Chao, Ying, Pastorino, Sandra, Jiang, Pengfei, Pingle, Sandeep C., Wrasidlo, Wolf, Makale, Milan
Publicado em 2014

Molecular determinants of α–synuclein mutants’ oligomerization and membrane interactions

Por Tsigelny, Igor F., Sharikov, Yuriy, Kouznetsova, Valentina L., Greenberg, Jerry P., Wrasidlo, Wolf, Overk, Cassia, Gonzalez, Tania, Trejo, Margarita, Spencer, Brian, Kosberg, Kori, Masliah, Eliezer
Publicado no ACS Chem Neurosci (2015)

Neuroprotective effects of the anti‐cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders

Por Wrasidlo, Wolf, Crews, Leslie A, Tsigelny, Igor F, Stocking, Emily, Kouznetsova, Valentina L, Price, Diana, Paulino, Amy, Gonzales, Tania, Overk, Cassia R, Patrick, Christina, Rockenstein, Edward, Masliah, Eliezer
Publicado no Br J Pharmacol (2014)

Structural diversity of Alzheimer’s disease Aβ dimers and their role in oligomerization and fibril formation

Por Tsigelny, Igor F., Sharikov, Yuriy, Kouznetsova, Valentina L., Greenberg, Jerry P., Wrasidlo, Wolfgang, Gonzalez, Tania, Desplats, Paula, Michael, Sarah E., Trejo-Morales, Margarita, Overk, Cassia R., Masliah, Eliezer
Publicado no J Alzheimers Dis (2014)

Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands

Por Nour, Afshin, Hayashi, Tomoko, Chan, Michael, Yao, Shiyin, Tawatao, Rommel I., Crain, Brian, Tsigelny, Igor F., Kouznetsova, Valentina L., Ahmadiiveli, Alast, Messer, Karen, Pu, Minya, Corr, Maripat, Carson, Dennis A., Cottam, Howard B.
Publicado no Bioorg Med Chem Lett (2014)

Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma

Por Tsigelny, Igor F., Mukthavaram, Rajesh, Kouznetsova, Valentina L., Chao, Ying, Babic, Ivan, Nurmemmedov, Elmar, Pastorino, Sandra, Jiang, Pengfei, Calligaris, David, Agar, Nathalie, Scadeng, Miriam, Pingle, Sandeep C., Wrasidlo, Wolfgang, Makale, Milan T., Kesari, Santosh
Publicado no Oncotarget (2015)

Identification of Substituted Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands

Por Chan, Michael, Hayashi, Tomoko, Mathewson, Richard D., Nour, Afshin, Hayashi, Yuki, Yao, Shiyin, Tawatao, Rommel I., Crain, Brian, Tsigelny, Igor F., Kouznetsova, Valentina L., Messer, Karen, Pu, Minya, Corr, Maripat, Carson, Dennis A., Cottam, Howard B.
Publicado em 2013