DEVELOPMENT OF NOVEL SMALL MOLECULES THAT TARGET GLIOBLASTOMA STEM CELLS

BACKGROUND: Transcription factors (TFs) are a major class of protein signaling molecules that play a critical role in most cancers. OLIG2 is a bHLH TF essential for survival and expansion of the highly aggressive brain cancer, glioblastoma (GBM), and represents an attractive therapeutic target. TFs...

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Main Authors: Kesari, Santosh, Tsigelny, Igor F., Mukthavaram, Rajesh, Kouznetsova, Valentina L., Chao, Ying, Pastorino, Sandra, Jiang, Pengfei, Pingle, Sandeep C., Wrasidlo, Wolf, Makale, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144530/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.61
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