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Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma
Transcription factors (TFs) are a major class of protein signaling molecules that play key cellular roles in cancers such as the highly lethal brain cancer—glioblastoma (GBM). However, the development of specific TF inhibitors has proved difficult owing to expansive protein-protein interfaces and th...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410230/ https://ncbi.nlm.nih.gov/pubmed/26517684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.5633 |
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