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Structural diversity of Alzheimer’s disease Aβ dimers and their role in oligomerization and fibril formation
Alzheimer’s disease (AD) is associated with the formation of toxic Aβ(42) oligomers and recent evidence supports a role for Aβ dimers as building blocks for oligomers. Molecular dynamics (MD) simulation studies have identified clans for the dominant conformations of Aβ(42) forming dimers; however, i...
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| Publicado en: | J Alzheimers Dis |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449729/ https://ncbi.nlm.nih.gov/pubmed/24240640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-131589 |
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