Загрузка...

Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation

Parkinson’s disease (PD) and Dementia with Lewy bodies are common disorders of the aging population characterized by the progressive accumulation of α-synuclein (α-syn) in the CNS. Aggregation of α-syn into oligomers with a ring-like appearance has been proposed a role in toxicity. However, the mole...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Tsigelny, Igor F., Sharikov, Yuriy, Wrasidlo, Wolfgang, Gonzalez, Tania, Desplats, Paula A., Crews, Leslie, Spencer, Brian, Masliah, Eliezer
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925782/
https://ncbi.nlm.nih.gov/pubmed/22251432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08489.x
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!