MECHANISM OF ALPHA-SYNUCLEIN OLIGOMERIZATION AND MEMBRANE INTERACTION: THEORETICAL APPROACH TO UNSTRUCTURED PROTEINS STUDIES

Misfolding and oligomerization of unstructured proteins is involved in the pathogenesis of Parkinson’s (PD), Alzheimer’s (AD), Huntington’s, and other neurodegenerative disorders. Elucidation of possible conformations of these proteins and their interactions with the membrane is necessary to underst...

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Bibliografiske detaljer
Main Authors: Tsigelny, Igor F., Sharikov, Yuriy, Miller, Mark A., Masliah, Eliezer
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627560/
https://ncbi.nlm.nih.gov/pubmed/18640077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.05.005
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