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MECHANISM OF ALPHA-SYNUCLEIN OLIGOMERIZATION AND MEMBRANE INTERACTION: THEORETICAL APPROACH TO UNSTRUCTURED PROTEINS STUDIES

Misfolding and oligomerization of unstructured proteins is involved in the pathogenesis of Parkinson’s (PD), Alzheimer’s (AD), Huntington’s, and other neurodegenerative disorders. Elucidation of possible conformations of these proteins and their interactions with the membrane is necessary to underst...

詳細記述

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書誌詳細
主要な著者: Tsigelny, Igor F., Sharikov, Yuriy, Miller, Mark A., Masliah, Eliezer
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627560/
https://ncbi.nlm.nih.gov/pubmed/18640077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.05.005
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