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MECHANISM OF ALPHA-SYNUCLEIN OLIGOMERIZATION AND MEMBRANE INTERACTION: THEORETICAL APPROACH TO UNSTRUCTURED PROTEINS STUDIES

Misfolding and oligomerization of unstructured proteins is involved in the pathogenesis of Parkinson’s (PD), Alzheimer’s (AD), Huntington’s, and other neurodegenerative disorders. Elucidation of possible conformations of these proteins and their interactions with the membrane is necessary to underst...

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Hlavní autoři: Tsigelny, Igor F., Sharikov, Yuriy, Miller, Mark A., Masliah, Eliezer
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627560/
https://ncbi.nlm.nih.gov/pubmed/18640077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.05.005
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