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MECHANISM OF ALPHA-SYNUCLEIN OLIGOMERIZATION AND MEMBRANE INTERACTION: THEORETICAL APPROACH TO UNSTRUCTURED PROTEINS STUDIES

Misfolding and oligomerization of unstructured proteins is involved in the pathogenesis of Parkinson’s (PD), Alzheimer’s (AD), Huntington’s, and other neurodegenerative disorders. Elucidation of possible conformations of these proteins and their interactions with the membrane is necessary to underst...

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Detalhes bibliográficos
Main Authors: Tsigelny, Igor F., Sharikov, Yuriy, Miller, Mark A., Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627560/
https://ncbi.nlm.nih.gov/pubmed/18640077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.05.005
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