Dynamic Cross Talk between S1P and CXCL12 Regulates Hematopoietic Stem Cells Migration, Development and Bone Remodeling

by Golan, Karin, Kollet, Orit, Lapidot, Tsvee
Published 2013

Regulation of long-term repopulating hematopoietic stem cells by EPCR/PAR1 signaling

by Gur-Cohen, Shiri, Kollet, Orit, Graf, Claudine, Esmon, Charles T., Ruf, Wolfram, Lapidot, Tsvee
Published in Ann N Y Acad Sci (2016)

Reactive Oxygen Species Regulate Hematopoietic Stem Cell Self-Renewal, Migration and Development, As Well As Their Bone Marrow Microenvironment

by Ludin, Aya, Gur-Cohen, Shiri, Golan, Karin, Kaufmann, Kerstin B., Itkin, Tomer, Medaglia, Chiara, Lu, Xin-Jiang, Ledergor, Guy, Kollet, Orit, Lapidot, Tsvee
Published 2014

CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules

by Shivtiel, Shoham, Kollet, Orit, Lapid, Kfir, Schajnovitz, Amir, Goichberg, Polina, Kalinkovich, Alexander, Shezen, Elias, Tesio, Melania, Netzer, Neta, Petit, Isabelle, Sharir, Amnon, Lapidot, Tsvee
Published 2008

PAR1 Expression Predicts Clinical G-CSF CD34(+) HSPC Mobilization and Repopulation Potential in Transplanted Patients

by Nevo, Neta, Zuckerman, Tsila, Gur-Cohen, Shiri, Kollet, Orit, Avemaria, Francesca, Shpall, Elizabeth J., Mendt, Mayela C., Nagler, Arnon, Brenner, Benjamin, Ben Arush, Myriam, Lapidot, Tsvee
Published in Hemasphere (2019)

Heparanase regulates retention and proliferation of primitive Sca-1(+)/c-Kit(+)/Lin(−) cells via modulation of the bone marrow microenvironment

by Spiegel, Asaf, Zcharia, Eyal, Vagima, Yaron, Itkin, Tomer, Kalinkovich, Alexander, Dar, Ayelet, Kollet, Orit, Netzer, Neta, Golan, Karin, Shafat, Itay, Ilan, Neta, Nagler, Arnon, Vlodavsky, Israel, Lapidot, Tsvee
Published 2008

S1P promotes murine progenitor cell egress and mobilization via S1P(1)-mediated ROS signaling and SDF-1 release

by Golan, Karin, Vagima, Yaron, Ludin, Aya, Itkin, Tomer, Cohen-Gur, Shiri, Kalinkovich, Alexander, Kollet, Orit, Kim, Chihwa, Schajnovitz, Amir, Ovadya, Yossi, Lapid, Kfir, Shivtiel, Shoham, Morris, Andrew J., Ratajczak, Mariusz Z., Lapidot, Tsvee
Published 2012

PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells

by Gur-Cohen, Shiri, Itkin, Tomer, Chakrabarty, Sagarika, Graf, Claudine, Kollet, Orit, Ludin, Aya, Golan, Karin, Kalinkovich, Alexander, Ledergor, Guy, Wong, Eitan, Niemeyer, Elisabeth, Porat, Ziv, Erez, Ayelet, Sagi, Irit, Esmon, Charles T, Ruf, Wolfram, Lapidot, Tsvee
Published in Nat Med (2015)

MT1-MMP and RECK are involved in human CD34(+) progenitor cell retention, egress, and mobilization

by Vagima, Yaron, Avigdor, Abraham, Goichberg, Polina, Shivtiel, Shoham, Tesio, Melania, Kalinkovich, Alexander, Golan, Karin, Dar, Ayelet, Kollet, Orit, Petit, Isabelle, Perl, Orly, Rosenthal, Ester, Resnick, Igor, Hardan, Izhar, Gellman, Yechiel N., Naor, David, Nagler, Arnon, Lapidot, Tsvee
Published 2009

Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation

by Orlovsky, Kira, Kalinkovich, Alexander, Rozovskaia, Tanya, Shezen, Elias, Itkin, Tomer, Alder, Hansjuerg, Ozer, Hatice Gulcin, Carramusa, Letizia, Avigdor, Abraham, Volinia, Stefano, Buchberg, Arthur, Mazo, Alex, Kollet, Orit, Largman, Corey, Croce, Carlo M., Nakamura, Tatsuya, Lapidot, Tsvee, Canaani, Eli
Published 2011

HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34(+) stem cell recruitment to the liver

by Kollet, Orit, Shivtiel, Shoham, Chen, Yuan-Qing, Suriawinata, Jenny, Thung, Swan N., Dabeva, Mariana D., Kahn, Joy, Spiegel, Asaf, Dar, Ayelet, Samira, Sarit, Goichberg, Polina, Kalinkovich, Alexander, Arenzana-Seisdedos, Fernando, Nagler, Arnon, Hardan, Izhar, Revel, Michel, Shafritz, David A., Lapidot, Tsvee
Published 2003

Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma

by Golan, Karin, Singh, Abhishek K., Kollet, Orit, Bertagna, Mayla, Althoff, Mark J., Khatib-Massalha, Eman, Petrovich-Kopitman, Ekaterina, Wellendorf, Ashley M., Massalha, Hassan, Levin-Zaidman, Smadar, Dadosh, Tali, Bohan, Breanna, V. Gawali, Mruniya, Dasgupta, Biplab, Lapidot, Tsvee, Cancelas, Jose A.
Published in Blood (2020)

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

by Dar, Ayelet, Schajnovitz, Amir, Lapid, Kfir, Kalinkovich, Alexander, Itkin, Tomer, Ludin, Aya, Kao, Wei-Ming, Battista, Michela, Tesio, Melania, Kollet, Orit, Cohen, Neta Netzer, Margalit, Raanan, Buss, Eike C., Baleux, Francoise, Oishi, Shinya, Fujii, Nobutaka, Larochelle, Andre, Dunbar, Cynthia E., Broxmeyer, Hal E., Frenette, Paul S., Lapidot, Tsvee
Published 2011

Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling

by Khatib-Massalha, Eman, Bhattacharya, Suditi, Massalha, Hassan, Biram, Adi, Golan, Karin, Kollet, Orit, Kumari, Anju, Avemaria, Francesca, Petrovich-Kopitman, Ekaterina, Gur-Cohen, Shiri, Itkin, Tomer, Brandenburger, Isabell, Spiegel, Asaf, Shulman, Ziv, Gerhart-Hines, Zachary, Itzkovitz, Shalev, Gunzer, Matthias, Offermanns, Stefan, Alon, Ronen, Ariel, Amiram, Lapidot, Tsvee
Published in Nat Commun (2020)

Distinct bone marrow blood vessels differentially regulate hematopoiesis

by Itkin, Tomer, Gur-Cohen, Shiri, Spencer, Joel A., Schajnovitz, Amir, Ramasamy, Saravana K., Kusumbe, Anjali P., Ledergor, Guy, Jung, Yookyung, Milo, Idan, Poulos, Michael G., Kalinkovich, Alexander, Ludin, Aya, Kollet, Orit, Shakhar, Guy, Butler, Jason M., Rafii, Shahin, Adams, Ralf H., Scadden, David T., Lin, Charles P., Lapidot, Tsvee
Published in Nature (2016)