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Dynamic Cross Talk between S1P and CXCL12 Regulates Hematopoietic Stem Cells Migration, Development and Bone Remodeling

Hematopoietic stem cells (HSCs) are mostly retained in a quiescent non-motile mode in their bone marrow (BM) niches, shifting to a migratory cycling and differentiating state to replenish the blood with mature leukocytes on demand. The balance between the major chemo-attractants CXCL12, predominantl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Golan, Karin, Kollet, Orit, Lapidot, Tsvee
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818832/
https://ncbi.nlm.nih.gov/pubmed/24276423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6091145
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