Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma

The fate of hematopoietic stem and progenitor cells (HSPC) is tightly regulated by their bone marrow (BM) microenvironment (ME). BM transplantation (BMT) frequently requires irradiation preconditioning to ablate endogenous hematopoietic cells. Whether the stromal ME is damaged and how it recovers af...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Golan, Karin, Singh, Abhishek K., Kollet, Orit, Bertagna, Mayla, Althoff, Mark J., Khatib-Massalha, Eman, Petrovich-Kopitman, Ekaterina, Wellendorf, Ashley M., Massalha, Hassan, Levin-Zaidman, Smadar, Dadosh, Tali, Bohan, Breanna, V. Gawali, Mruniya, Dasgupta, Biplab, Lapidot, Tsvee, Cancelas, Jose A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735163/
https://ncbi.nlm.nih.gov/pubmed/32929449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005399
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