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Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma

The fate of hematopoietic stem and progenitor cells (HSPC) is tightly regulated by their bone marrow (BM) microenvironment (ME). BM transplantation (BMT) frequently requires irradiation preconditioning to ablate endogenous hematopoietic cells. Whether the stromal ME is damaged and how it recovers af...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Golan, Karin, Singh, Abhishek K., Kollet, Orit, Bertagna, Mayla, Althoff, Mark J., Khatib-Massalha, Eman, Petrovich-Kopitman, Ekaterina, Wellendorf, Ashley M., Massalha, Hassan, Levin-Zaidman, Smadar, Dadosh, Tali, Bohan, Breanna, V. Gawali, Mruniya, Dasgupta, Biplab, Lapidot, Tsvee, Cancelas, Jose A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735163/
https://ncbi.nlm.nih.gov/pubmed/32929449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005399
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