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Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling
Neutrophils provide first line of host defense against bacterial infections utilizing glycolysis for their effector functions. How glycolysis and its major byproduct lactate are triggered in bone marrow (BM) neutrophils and their contribution to neutrophil mobilization in acute inflammation is not c...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7363928/ https://ncbi.nlm.nih.gov/pubmed/32669546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17402-2 |
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