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SNARE priming is essential for maturation of autophagosomes but not for their formation

Autophagy, a unique intracellular membrane-trafficking pathway, is initiated by the formation of an isolation membrane (phagophore) that engulfs cytoplasmic constituents, leading to generation of the autophagosome, a double-membrane vesicle, which is targeted to the lysosome. The outer autophagosoma...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Abada, Adi, Levin-Zaidman, Smadar, Porat, Ziv, Dadosh, Tali, Elazar, Zvulun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715740/
https://ncbi.nlm.nih.gov/pubmed/29138318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705572114
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