LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

Autophagy, a critical process for bulk degradation of proteins and organelles, requires conjugation of Atg8 proteins to phosphatidylethanolamine on the autophagic membrane. At least eight different Atg8 orthologs belonging to two subfamilies (LC3 and GATE-16/GABARAP) occur in mammalian cells, but th...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Weidberg, Hilla, Shvets, Elena, Shpilka, Tomer, Shimron, Frida, Shinder, Vera, Elazar, Zvulun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885923/
https://ncbi.nlm.nih.gov/pubmed/20418806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.74
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky