CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules

The CD45 phosphatase is uniquely expressed by all leukocytes, but its role in regulating hematopoietic progenitors is poorly understood. We show that enhanced CD45 expression on bone marrow (BM) leukocytes correlates with increased cell motility in response to stress signals. Moreover, immature CD45...

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Autori principali: Shivtiel, Shoham, Kollet, Orit, Lapid, Kfir, Schajnovitz, Amir, Goichberg, Polina, Kalinkovich, Alexander, Shezen, Elias, Tesio, Melania, Netzer, Neta, Petit, Isabelle, Sharir, Amnon, Lapidot, Tsvee
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556782/
https://ncbi.nlm.nih.gov/pubmed/18779349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080072
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