Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

Steady-state egress of hematopoietic progenitor cells can be rapidly amplified by mobilizing agents such as AMD3100, the mechanism, however, is poorly understood. We report that AMD3100 increased the homeostatic release of the chemokine SDF-1 to the circulation in mice and non-human primates. Neutra...

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書誌詳細
主要な著者: Dar, Ayelet, Schajnovitz, Amir, Lapid, Kfir, Kalinkovich, Alexander, Itkin, Tomer, Ludin, Aya, Kao, Wei-Ming, Battista, Michela, Tesio, Melania, Kollet, Orit, Cohen, Neta Netzer, Margalit, Raanan, Buss, Eike C., Baleux, Francoise, Oishi, Shinya, Fujii, Nobutaka, Larochelle, Andre, Dunbar, Cynthia E., Broxmeyer, Hal E., Frenette, Paul S., Lapidot, Tsvee
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175714/
https://ncbi.nlm.nih.gov/pubmed/21494253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.62
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