Role of HLA Adaptation in HIV Evolution

door Kløverpris, Henrik N., Leslie, Alasdair, Goulder, Philip
Gepubliceerd in Front Immunol (2016)

Type 3 ILCs in Lung Disease

door Ardain, Amanda, Porterfield, James Zachary, Kløverpris, Henrik N., Leslie, Alasdair
Gepubliceerd in Front Immunol (2019)

Immune hierarchy among HIV-1 CD8(+) T cell epitopes delivered by dendritic cells depends on MHC-I binding irrespective of mode of loading and immunization in HLA-A*0201 mice

door KLOVERPRIS, HENRIK N, KARLSSON, INGRID, THORN, METTE, BUUS, SØREN, FOMSGAARD, ANDERS
Gepubliceerd in 2009

A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape

door Kløverpris, Henrik N, Cole, David K, Fuller, Anna, Carlson, Jonathan, Beck, Konrad, Schauenburg, Andrea J, Rizkallah, Pierre J, Buus, Søren, Sewell, Andrew K, Goulder, Philip
Gepubliceerd in Retrovirology (2015)

Early Antigen Presentation of Protective HIV-1 KF11Gag and KK10Gag Epitopes from Incoming Viral Particles Facilitates Rapid Recognition of Infected Cells by Specific CD8(+) T Cells

door Kløverpris, Henrik N., Payne, Rebecca P., Sacha, Jonah B., Rasaiyaah, Jane T., Chen, Fabian, Takiguchi, Masafumi, Yang, Otto O., Towers, Greg J., Goulder, Philip, Prado, Julia G.
Gepubliceerd in 2013

HLA-Specific Intracellular Epitope Processing Shapes an Immunodominance Pattern for HLA-B*57 That Is Distinct from HLA-B*58:01

door Kløverpris, Henrik N., Stryhn, Anette, Harndahl, Mikkel, Payne, Rebecca, Towers, Greg J., Chen, Fabian, Riddell, Lynn, Walker, Bruce D., Ndung'u, Thumbi, Leslie, Alasdair, Buus, Søren, Goulder, Philip
Gepubliceerd in 2013

Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals

door Kløverpris, Henrik N., Jackson, Akil, Handley, Amanda, Hayes, Peter, Gilmour, Jill, Riddell, Lynn, Chen, Fabian, Atkins, Mark, Boffito, Marta, Walker, Bruce D., Ackland, Jim, Sullivan, Mark, Goulder, Philip
Gepubliceerd in 2013

Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life

door Attaf, Meriem, Roider, Julia, Malik, Amna, Rius Rafael, Cristina, Dolton, Garry, Prendergast, Andrew J., Leslie, Alasdair, Ndung'u, Thumbi, Kløverpris, Henrik N., Sewell, Andrew K., Goulder, Philip J.
Gepubliceerd in Front Immunol (2020)

Corrigendum: Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life

door Attaf, Meriem, Roider, Julia, Malik, Amna, Rafael, Cristina Rius, Dolton, Garry, Prendergast, Andrew J., Leslie, Alasdair, Ndung’u, Thumbi, Kløverpris, Henrik N., Sewell, Andrew K., Goulder, Philip J.
Gepubliceerd in Front Immunol (2020)

Major TCR Repertoire Perturbation by Immunodominant HLA-B(*)44:03-Restricted CMV-Specific T Cells

door Attaf, Meriem, Malik, Amna, Severinsen, Mai C., Roider, Julia, Ogongo, Paul, Buus, Søren, Ndung'u, Thumbi, Leslie, Alasdair, Kløverpris, Henrik N., Matthews, Philippa C., Sewell, Andrew K., Goulder, Philip
Gepubliceerd in Front Immunol (2018)

HLA-A*68:02-restricted Gag-specific CTL responses can drive selection pressure on HIV but are subdominant and ineffective

door Kløverpris, Henrik N., Stryhn, Anette, Harndahl, Mikkel, Carlson, Jonathan M., Leslie, Alasdair J, Chen, Fabian, Riddell, Lynn, Mulenga, Joseph, Walker, Bruce D., Ndung’u, Thumbi, Buus, Søren, Goulder, Philip
Gepubliceerd in AIDS (2013)

A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individua...

door Jackson, Akil, Kløverpris, Henrik N., Boffito, Marta, Handley, Amanda, Atkins, Mark, Hayes, Peter, Gilmour, Jill, Riddel, Lynn, Chen, Fabian, Bailey-Tippets, Melanie, Walker, Bruce, Ackland, Jim, Sullivan, Mark, Goulder, Philip
Gepubliceerd in 2013

HIV Subtype Influences HLA-B*07:02-Associated HIV Disease Outcome

door Kløverpris, Henrik N., Adland, Emily, Koyanagi, Madoka, Stryhn, Anette, Harndahl, Mikkel, Matthews, Philippa C., Shapiro, Roger, Walker, Bruce D., Ndung'u, Thumbi, Brander, Christian, Takiguchi, Masafumi, Buus, Søren, Goulder, Philip
Gepubliceerd in 2014

HLA-B*57 Micropolymorphism Shapes HLA Allele-Specific Epitope Immunogenicity, Selection Pressure, and HIV Immune Control

door Kloverpris, Henrik N., Stryhn, Anette, Harndahl, Mikkel, van der Stok, Mary, Payne, Rebecca P., Matthews, Philippa C., Chen, Fabian, Riddell, Lynn, Walker, Bruce D., Ndung'u, Thumbi, Buus, Søren, Goulder, Philip
Gepubliceerd in 2012

Nonhuman TRIM5 Variants Enhance Recognition of HIV-1-Infected Cells by CD8(+) T Cells

door Jimenez-Moyano, Esther, Ruiz, Alba, Kløverpris, Henrik N., Rodriguez-Plata, Maria T., Peña, Ruth, Blondeau, Caroline, Selwood, David L., Izquierdo-Useros, Nuria, Moris, Arnaud, Clotet, Bonaventura, Goulder, Philip, Towers, Greg J., Prado, Julia G.
Gepubliceerd in J Virol (2016)

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

door Nunes-Alves, Cláudio, Booty, Matthew G., Carpenter, Stephen M., Rothchild, Alissa C., Martin, Constance J., Desjardins, Danielle, Steblenko, Katherine, Kløverpris, Henrik N., Madansein, Rajhmun, Ramsuran, Duran, Leslie, Alasdair, Correia-Neves, Margarida, Behar, Samuel M.
Gepubliceerd in PLoS Pathog (2015)

Programmed death-1 expression on HIV-1-specific CD8(+) T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

door Kløverpris, Henrik N., McGregor, Reuben, McLaren, James E., Ladell, Kristin, Stryhn, Anette, Koofhethile, Catherine, Brener, Jacqui, Chen, Fabian, Riddell, Lynn, Graziano, Luzzi, Klenerman, Paul, Leslie, Alasdair, Buus, Søren, Price, David A., Goulder, Philip
Gepubliceerd in 2014

Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

door Singh, Alveera, Kazer, Samuel W., Roider, Julia, Krista, Kami C., Millar, Jane, Asowata, Osaretin E., Ngoepe, Abigail, Ramsuran, Duran, Fardoos, Rabiah, Ardain, Amanda, Muenchhoff, Maximilian, Kuhn, Warren, Karim, Farina, Ndung’u, Thumbi, Shalek, Alex K., Goulder, Philip, Leslie, Alasdair, Kløverpris, Henrik N.
Gepubliceerd in Cell Rep (2020)

HIV Control through a Single Nucleotide on the HLA-B Locus

door Kløverpris, Henrik N., Harndahl, Mikkel, Leslie, Alasdair J., Carlson, Jonathan M., Ismail, Nasreen, van der Stok, Mary, Huang, Kuan-Hsiang Gary, Chen, Fabian, Riddell, Lynn, Steyn, Dewald, Goedhals, Dominique, van Vuuren, Cloete, Frater, John, Walker, Bruce D., Carrington, Mary, Ndung'u, Thumbi, Buus, Søren, Goulder, Philip
Gepubliceerd in 2012

CD8(+) T-cell receptor bias and immundominance in HIV-1 infection

door Kløverpris, Henrik N., McGregor, Reuben, McLaren, James E., Ladell, Kristin, Harndahl, Mikkel, Stryhn, Anette, Carlson, Jonathan, Koofhethile, Catherine, Gerritsen, Bram, Kesmir, Can, Chen, Fabian, Riddell, Lynn, Luzzi, Graz, Leslie, Alasdair, Walker, Bruce D., Ndung'u, Thumbi, Buus, Søren, Price, David A., Goulder, Philip J.
Gepubliceerd in J Immunol (2015)