Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life

Human cytomegalovirus (CMV) is a highly prevalent herpesvirus, particularly in sub-Saharan Africa, where it is endemic from infancy. The T cell response against CMV is important in keeping the virus in check, with CD8 T cells playing a major role in the control of CMV viraemia. Human leukocyte antig...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Attaf, Meriem, Roider, Julia, Malik, Amna, Rius Rafael, Cristina, Dolton, Garry, Prendergast, Andrew J., Leslie, Alasdair, Ndung'u, Thumbi, Kløverpris, Henrik N., Sewell, Andrew K., Goulder, Philip J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554308/
https://ncbi.nlm.nih.gov/pubmed/33101265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01587
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