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Role of HLA Adaptation in HIV Evolution
Killing of HIV-infected cells by CD8(+) T-cells imposes strong selection pressure on the virus toward escape. The HLA class I molecules that are successful in mediating some degree of control over the virus are those that tend to present epitopes in conserved regions of the proteome, such as in p24...
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| Publicado en: | Front Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4716577/ https://ncbi.nlm.nih.gov/pubmed/26834742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00665 |
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