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Role of HLA Adaptation in HIV Evolution
Killing of HIV-infected cells by CD8(+) T-cells imposes strong selection pressure on the virus toward escape. The HLA class I molecules that are successful in mediating some degree of control over the virus are those that tend to present epitopes in conserved regions of the proteome, such as in p24...
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Publicado no: | Front Immunol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4716577/ https://ncbi.nlm.nih.gov/pubmed/26834742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00665 |
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