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Adaptive Evolution of HIV at HLA Epitopes Is Associated with Ethnicity in Canada
Host immune selection pressure influences the development of mutations that allow for HIV escape. Mutation patterns induced in HIV by the human leukocyte antigen (HLA) are HLA-allele specific. As ethnic groups have distinct and characteristic HLA allele frequencies, we can expect divergent viral evo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365047/ https://ncbi.nlm.nih.gov/pubmed/22693560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036933 |
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