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Both Epistasis and Diversifying Selection Drive the Structural Evolution of the Ebola Virus Glycoprotein Mucin-Like Domain

Throughout the last 3 decades, Ebola virus (EBOV) outbreaks have been confined to isolated areas within Central Africa; however, the 2014 variant reached unprecedented transmission and mortality rates. While the outbreak was still under way, it was reported that the variant leading up to this outbre...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ibeh, Neke, Nshogozabahizi, Jean Claude, Aris-Brosou, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934740/
https://ncbi.nlm.nih.gov/pubmed/27009964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00322-16
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