Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

The immune system can recognize virtually any antigen, yet T cell responses against several pathogens, including Mycobacterium tuberculosis, are restricted to a limited number of immunodominant epitopes. The host factors that affect immunodominance are incompletely understood. Whether immunodominant...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Nunes-Alves, Cláudio, Booty, Matthew G., Carpenter, Stephen M., Rothchild, Alissa C., Martin, Constance J., Desjardins, Danielle, Steblenko, Katherine, Kløverpris, Henrik N., Madansein, Rajhmun, Ramsuran, Duran, Leslie, Alasdair, Correia-Neves, Margarida, Behar, Samuel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422591/
https://ncbi.nlm.nih.gov/pubmed/25945999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004849
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