Par6 family proteins in cancer

Por Marques, Elsa, Klefström, Juha
Publicado no Oncoscience (2015)

Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4

Por Partanen, Johanna I., Tervonen, Topi A., Klefström, Juha
Publicado em 2013

MYC and AMPK–Save Energy or Die!

Por Haikala, Heidi M., Anttila, Johanna M., Klefström, Juha
Publicado no Front Cell Dev Biol (2017)

c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis

Por Nieminen, Anni I, Partanen, Johanna I, Hau, Annika, Klefstrom, Juha
Publicado em 2007

MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures

Por Haikala, Heidi M., Klefström, Juha, Eilers, Martin, Wiese, Katrin E.
Publicado no Cell Cycle (2016)

Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization

Por Partanen, Johanna I., Nieminen, Anni I., Mäkelä, Tomi P., Klefstrom, Juha
Publicado em 2007

Data integration to prioritize drugs using genomics and curated data

Por Louhimo, Riku, Laakso, Marko, Belitskin, Denis, Klefström, Juha, Lehtonen, Rainer, Hautaniemi, Sampsa
Publicado no BioData Min (2016)

Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer

Por Heinonen, Henna, Nieminen, Anni, Saarela, Matti, Kallioniemi, Anne, Klefström, Juha, Hautaniemi, Sampsa, Monni, Outi
Publicado em 2008

Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

Por Nieminen, Anni I., Eskelinen, Vilja M., Haikala, Heidi M., Tervonen, Topi A., Yan, Yan, Partanen, Johanna I., Klefström, Juha
Publicado em 2013

Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells

Por Wiese, Katrin E, Haikala, Heidi M, von Eyss, Björn, Wolf, Elmar, Esnault, Cyril, Rosenwald, Andreas, Treisman, Richard, Klefström, Juha, Eilers, Martin
Publicado no EMBO J (2015)

Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity

Por Partanen, Johanna I., Tervonen, Topi A., Myllynen, Mikko, Lind, Essi, Imai, Misa, Katajisto, Pekka, Dijkgraaf, Gerrit J. P., Kovanen, Panu E., Mäkelä, Tomi P., Werb, Zena, Klefström, Juha
Publicado em 2012

Serine 62 phosphorylated MYC associates with nuclear lamins and its regulation by CIP2A is essential for regenerative proliferation

Por Myant, Kevin, Qiao, Xi, Halonen, Tuuli, Come, Christophe, Laine, Anni, Janghorban, Mahnaz, Partanen, Johanna I., Cassidy, John, Ogg, Erin-Lee, Cammareri, Patrizia, Laiterä, Tiina, Okkeri, Juha, Klefström, Juha, Sears, Rosalie C., Sansom, Owen J., Westermarck, Jukka
Publicado no Cell Rep (2015)

Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells

Por Khanna, Anchit, Kauko, Otto, Böckelman, Camilla, Laine, Anni, Schreck, Ilona, Partanen, Johanna I., Szwajda, Agnieszka, Bormann, Stefanie, Bilgen, Turker, Helenius, Merja, Pokharel, Yuba R., Pimanda, John, Russel, Mike R., Haglund, Caj, Cole, Kristina A., Klefström, Juha, Aittokallio, Tero, Weiss, Carsten, Ristimäki, Ari, Visakorpi, Tapio, Westermarck, Jukka
Publicado em 2013