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Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4

The PAR clan of polarity regulating genes was initially discovered in a genetic screen searching for genes involved in asymmetric cell divisions in the Caenorhabditis elegans embryo. Today, investigations in worms, flies and mammals have established PAR proteins as conserved and fundamental regulato...

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Autori principali: Partanen, Johanna I., Tervonen, Topi A., Klefström, Juha
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785967/
https://ncbi.nlm.nih.gov/pubmed/24062587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0111
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