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Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4

The PAR clan of polarity regulating genes was initially discovered in a genetic screen searching for genes involved in asymmetric cell divisions in the Caenorhabditis elegans embryo. Today, investigations in worms, flies and mammals have established PAR proteins as conserved and fundamental regulato...

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Detalhes bibliográficos
Main Authors: Partanen, Johanna I., Tervonen, Topi A., Klefström, Juha
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785967/
https://ncbi.nlm.nih.gov/pubmed/24062587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0111
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