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MYC and AMPK–Save Energy or Die!
MYC sustains non-stop proliferation by altering metabolic machinery to support growth of cell mass. As part of the metabolic transformation MYC promotes lipid, nucleotide and protein synthesis by hijacking citric acid cycle to serve biosynthetic processes, which simultaneously exhausts ATP productio...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386972/ https://ncbi.nlm.nih.gov/pubmed/28443281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00038 |
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