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Myc requires RhoA/SRF to reprogram glutamine metabolism
RhoA regulates actin cytoskeleton but recent evidence suggest a role for this conserved Rho GTPase also in other cellular processes, including transcriptional control of cell proliferation and survival. Interestingy, loss of RhoA is synthetic lethal with oncogenic Myc, a master transcription factor...
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| Publié dans: | Small GTPases |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5927483/ https://ncbi.nlm.nih.gov/pubmed/27532209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1224287 |
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