Myc requires RhoA/SRF to reprogram glutamine metabolism

RhoA regulates actin cytoskeleton but recent evidence suggest a role for this conserved Rho GTPase also in other cellular processes, including transcriptional control of cell proliferation and survival. Interestingy, loss of RhoA is synthetic lethal with oncogenic Myc, a master transcription factor...

Full description

Saved in:
Bibliographic Details
Published in:Small GTPases
Main Authors: Haikala, Heidi M., Marques, Elsa, Turunen, Mikko, Klefström, Juha
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927483/
https://ncbi.nlm.nih.gov/pubmed/27532209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1224287
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items