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MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures

Apoptosis caused by deregulated MYC expression is a prototype example of intrinsic tumor suppression. However, it is still unclear how supraphysiological MYC expression levels engage specific sets of target genes to promote apoptosis. Recently, we demonstrated that repression of SRF target genes by...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Haikala, Heidi M., Klefström, Juha, Eilers, Martin, Wiese, Katrin E.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943699/
https://ncbi.nlm.nih.gov/pubmed/26873145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121351
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