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MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures

Apoptosis caused by deregulated MYC expression is a prototype example of intrinsic tumor suppression. However, it is still unclear how supraphysiological MYC expression levels engage specific sets of target genes to promote apoptosis. Recently, we demonstrated that repression of SRF target genes by...

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Foilsithe in:Cell Cycle
Main Authors: Haikala, Heidi M., Klefström, Juha, Eilers, Martin, Wiese, Katrin E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943699/
https://ncbi.nlm.nih.gov/pubmed/26873145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121351
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