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MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures

Apoptosis caused by deregulated MYC expression is a prototype example of intrinsic tumor suppression. However, it is still unclear how supraphysiological MYC expression levels engage specific sets of target genes to promote apoptosis. Recently, we demonstrated that repression of SRF target genes by...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Cycle
Päätekijät: Haikala, Heidi M., Klefström, Juha, Eilers, Martin, Wiese, Katrin E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943699/
https://ncbi.nlm.nih.gov/pubmed/26873145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121351
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