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MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures

Apoptosis caused by deregulated MYC expression is a prototype example of intrinsic tumor suppression. However, it is still unclear how supraphysiological MYC expression levels engage specific sets of target genes to promote apoptosis. Recently, we demonstrated that repression of SRF target genes by...

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Bibliografski detalji
Izdano u:Cell Cycle
Glavni autori: Haikala, Heidi M., Klefström, Juha, Eilers, Martin, Wiese, Katrin E.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943699/
https://ncbi.nlm.nih.gov/pubmed/26873145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121351
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