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MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures

Apoptosis caused by deregulated MYC expression is a prototype example of intrinsic tumor suppression. However, it is still unclear how supraphysiological MYC expression levels engage specific sets of target genes to promote apoptosis. Recently, we demonstrated that repression of SRF target genes by...

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Опубликовано в: :Cell Cycle
Главные авторы: Haikala, Heidi M., Klefström, Juha, Eilers, Martin, Wiese, Katrin E.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943699/
https://ncbi.nlm.nih.gov/pubmed/26873145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121351
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