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MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures

Apoptosis caused by deregulated MYC expression is a prototype example of intrinsic tumor suppression. However, it is still unclear how supraphysiological MYC expression levels engage specific sets of target genes to promote apoptosis. Recently, we demonstrated that repression of SRF target genes by...

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Bibliografische gegevens
Gepubliceerd in:Cell Cycle
Hoofdauteurs: Haikala, Heidi M., Klefström, Juha, Eilers, Martin, Wiese, Katrin E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943699/
https://ncbi.nlm.nih.gov/pubmed/26873145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121351
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