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MYC and AMPK–Save Energy or Die!

MYC sustains non-stop proliferation by altering metabolic machinery to support growth of cell mass. As part of the metabolic transformation MYC promotes lipid, nucleotide and protein synthesis by hijacking citric acid cycle to serve biosynthetic processes, which simultaneously exhausts ATP productio...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Haikala, Heidi M., Anttila, Johanna M., Klefström, Juha
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386972/
https://ncbi.nlm.nih.gov/pubmed/28443281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00038
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