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c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis

Oncogenic c-Myc renders cells sensitive to TRAIL-induced apoptosis, and existing data suggest that c-Myc sensitizes cells to apoptosis by promoting activation of the mitochondrial apoptosis pathway. However, the molecular mechanisms linking the mitochondrial effects of c-Myc to the c-Myc-dependent s...

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Detalhes bibliográficos
Main Authors: Nieminen, Anni I, Partanen, Johanna I, Hau, Annika, Klefstrom, Juha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852827/
https://ncbi.nlm.nih.gov/pubmed/17268552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601551
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