Serine 62 phosphorylated MYC associates with nuclear lamins and its regulation by CIP2A is essential for regenerative proliferation

Understanding of the mechanisms determining MYC’s transcriptional -and proliferation promoting activities in vivo could facilitate approaches for MYC targeting. However, post-translational mechanisms that control MYC function in vivo are poorly understood. Here we demonstrate that MYC phosphorylatio...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Myant, Kevin, Qiao, Xi, Halonen, Tuuli, Come, Christophe, Laine, Anni, Janghorban, Mahnaz, Partanen, Johanna I., Cassidy, John, Ogg, Erin-Lee, Cammareri, Patrizia, Laiterä, Tiina, Okkeri, Juha, Klefström, Juha, Sears, Rosalie C., Sansom, Owen J., Westermarck, Jukka
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535171/
https://ncbi.nlm.nih.gov/pubmed/26235622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.003
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