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Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56
Protein phosphatase 2A (PP2A) is a critical human tumor suppressor. Cancerous inhibitor of PP2A (CIP2A) supports the activity of several critical cancer drivers (Akt, MYC, E2F1) and promotes malignancy in most cancer types via PP2A inhibition. However, the 3D structure of CIP2A has not been solved,...
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| Опубликовано в: : | EMBO Rep |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331240/ https://ncbi.nlm.nih.gov/pubmed/28174209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642788 |
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