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ETS1 Mediates MEK1/2-Dependent Overexpression of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Human Cancer Cells

EGFR-MEK-ERK signaling pathway has an established role in promoting malignant growth and disease progression in human cancers. Therefore identification of transcriptional targets mediating the oncogenic effects of the EGFR-MEK-ERK pathway would be highly relevant. Cancerous inhibitor of protein phos...

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Detalhes bibliográficos
Main Authors: Khanna, Anchit, Okkeri, Juha, Bilgen, Turker, Tiirikka, Timo, Vihinen, Mauno, Visakorpi, Tapio, Westermarck, Jukka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062549/
https://ncbi.nlm.nih.gov/pubmed/21445343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017979
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